Medidas lineales para medir la atrofia del núcleo caudado en la Enfermedad de Huntington

El índice anchura del asta frontal respecto a la distancia intercaudados decrece. Lo normal es entre 2.2 y 2.6.

Aprendiendo a visualizar el sistema glimfático por resonancia magnética

 

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Patrones de neuroimagen en las encefalopatías e intoxicaciones

 

Segmentos de troncos supraaórticos por angioTC

 

Diffusion-based tractography atlas of the human acoustic radiation

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Signo de la golondrina en la Enfermedad de Parkinson

Axial SWI Clinical high resolution 3D-T2*/SWI MRI (Philips ‘PRESTO’ sequence) of a Parkinson's disease patient showing absence of the normal high SWI signal within the nigrosome-1 bilaterally (absent swallow tail sign). Image and text used under creative commons licence CC BY 3.0. Original source: Schwarz ST, Afzal M, Morgan PS et-al. The 'swallow tail' appearance of the healthy nigrosome - a new accurate test of Parkinson's disease: a case-control and retrospective cross-sectional MRI study at 3T. PLoS ONE. 2014;9 (4): e93814. doi:10.1371/journal.pone.0093814 Clinical high resolution 3D-T2*/SWI MRI (Philips ‘PRESTO’ sequence) of a Parkinson's disease patient showing absence of the normal high SWI signal within the nigrosome-1 bilaterally (absent swallow tail sign). Image and text used under creative commons licence. Original source: Schwarz ST, Afzal M, Morgan PS et-al. The 'swallow tail' appearance of the healthy nigrosome - a new accurate test of Parkinson's disease: a case-control and retrospective cross-sectional MRI study at 3T. PLoS ONE. 2014;9 (4): e93814. doi:10.1371/journal.pone.0093814
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Abducens nerve on MRI

Annotated MRI (FIESTA)
Modality: MRI




MRI Axial T2 FIESTA
Annotated high resolution FIESTA sequence through the medulla and pons demonstrates the normal course of the abducens nerve (CN VI) (white arrow) as it ascends from the ponto-medullary junction to Dorello's canal.

Resonancia de 7T para detectar Enfermedad de Alzheimer

T2*-weighted (a and b), T2-weighted (c and d), and FLAIR (e and f) images of the medial temporal lobe obtained at 1.5 T (a, c, and e) and 7 T (b, d, and f), illustrating the strikingly improved resolution that high-field MRI offers. Reprinted from Theysohn et al.: The human hippocampus at 7 T-in vivo MRI, Hippocampus 19:1–7, 2009, copyright 2008, Wiley-Liss, Inc.

Five AD hippocampal specimens (A1–A5) and one normal control (N4) are shown. Note the signal voids in AD specimens along the hippocampus compared with the lack of such signal voids in the normal control. The border between field CA1 and the subiculum is indicated by the white line derived from coregistered acetylcholine, myelin, and Nissl staining. The variability in their locations relative to the medial aspect of the hippocampal body illustrates the challenges inherent in in vivo imaging studies of hippocampal subregions. Reprinted from Neurobiology of Aging, vol 36, Zeineh M, Chen Y, Kitzler HH, Hammond R, Vogel H, Rutt BK, “Activated iron-containing microglia in the human hippocampus identified by magnetic resonance imaging in Alzheimer’s disease,” pp 2483–2500, 2015, with permission from Elsevier.

7-T FLAIR MRI in the (left to right) transverse (left), sagittal (center), and coronal (right) views. The arrow is pointing to a microinfarct. Reprinted with permission from van Rooden S, Goos JD, van Opstal AM, Versluis MJ, Webb AG, Blauw GJ, et al: Increased number of microinfarcts in Alzheimer disease at 7-T MR imaging. Radiology 270:205–211, 2014.

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Midiendo el volumen del bulbo olfatorio como método diagnóstico para la Enfermedad de Parkinson

A. Paciente con Atrofia Multisistema, presenta una morfología del bulbo olfatorio normal.
B. Paciente con Parkinson, con reducción del volumen del bulbo.

El volumen del bulbo olfatorio permite ayudar a distinguir entre pacientes con Enfermedad de Parkinson y pacientes con Parkinsonismo (AMS, DCB, PSP).

DOI: http://dx.doi.org/10.1016/j.parkreldis.2015.05.001